CD29 antibodies, human

CD29 antibodies, human

Clone: REA1060 | Dilution: 1:50
Clone REA1060 recognizes the human CD29 antigen, a 130 kDa single-pass type I membrane protein. CD29 is also known as integrin β1 or GPIIa. It forms heterodimers with integrins α1-11 and αV to form functional integrin receptors which bind several cell surface and extracellular molecules such as collagen, fibronectin, laminin, VCAM1, cytotactin, osteopontin, epiligrin, thrombospondin, etc. The cytoplasmic domain of CD29 can interact with cytoskeletal proteins and signaling molecules. In humans, CD29 can be found in four different isoforms (β1A, β1B, β1C, β1D).
Additional information: Clone REA1060 displays negligible binding to Fc receptors.

Alternative names

ITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB

Technical specifications

  • Antigen: CD29
  • Clone: REA1060
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB
  • Entrez Gene ID: 3688
  • Molecular mass of antigen [kDa]: 86
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBright 515
  • Selected references

    1. Altruda, F. et al. (1990) A human integrin beta 1 subunit with a unique cytoplasmic domain generated by alternative mRNA processing. Gene 95: 261-266
    2. Shih, D. T. et al. (1993) Structure/function analysis of the integrin beta 1 subunit by epitope mapping. J. Cell Biol. 122(6): 1361-1371
    3. Brakebusch, C. et al. (1997) Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules. J. Cell. Sci. 110: 2895-2904
Product options: 6
130-118-194

CD29-PE, human

for 30
tests
(1)
-
130-118-121

CD29-PE, human

for 100
tests
(1)
-
130-118-195

CD29-APC, human

for 30
tests
(1)
-
130-118-122

CD29-APC, human

for 100
tests
(1)
-
130-118-199

CD29-VioBright 515, human

for 30
tests
(1)
-
130-118-126

CD29-VioBright 515, human

for 100
tests
(1)
-