CD283 (TLR3) antibodies, human

CD283 (TLR3) antibodies, human

Clone: TLR 3.7 | Dilution: 1:10
The monoclonal antibody TLR 3.7 reacts with CD283, also known as toll-like receptor 3 (TLR3). Toll-like receptors are a family of pattern recognition receptors that have evolved to detect components of foreign pathogens referred to as pathogenassociated molecular patterns. TLR3 is a single-pass type I membrane protein expressed exclusively in intracellular vesicles, such as the endoplasmic reticulum (ER), endosomes, lysosomes, and endolysosomes, where it recognizes microbial dsRNA. Multiple cell types are known to express TLR3 including dendritic cells, keratinocytes, and neurons. TLR3 activates via the TRIF-dependent pathway antiviral immune responses through the production of type I interferon and inflammatory cytokines, suggesting that TLR3 has an essential role in the prevention of viral infection.

Alternative Names

TLR3, IIAE2

Technical specifications

  • Antigen: CD283 (TLR3)
  • Clone: TLR 3.7
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: TLR3, IIAE2
  • Entrez Gene ID: 7098
  • Molecular mass of antigen [kDa]: 101
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: dendritic cells, epithelial cells, fibroblasts, pancreas, placenta
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
Product options: 7

Product information

Size
Order no.
Price

CD283 (TLR3)-FITC, human

  • TLR 3.7
  • 1:10
  • For research use only
for 30
tests
(1)
130-100-001
-

CD283 (TLR3)-FITC, human

  • TLR 3.7
  • 1:10
  • For research use only
for 100
tests
(1)
130-100-000
-

CD283 (TLR3)-PE, human

  • TLR 3.7
  • 1:10
  • For research use only
for 30
tests
(1)
130-100-304
-

CD283 (TLR3)-PE, human

  • TLR 3.7
  • 1:10
  • For research use only
for 100
tests
(1)
130-096-887
-

CD283 (TLR3)-APC, human

  • TLR 3.7
  • 1:10
  • For research use only
for 30
tests
(1)
130-100-383
-

CD283 (TLR3)-APC, human

  • TLR 3.7
  • 1:10
  • For research use only
for 100
tests
(1)
130-096-885
-

CD283 (TLR3)-Biotin, human

  • TLR 3.7
  • 1:10
  • For research use only
for 100
tests
(1)
130-096-889
-

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