CD279 (PD1) antibodies – functional grade, mouse

CD279 (PD1) antibodies – functional grade, mouse

Clone: HA2-7B1
CD279, also known as programmed death-1 (PD1), is a 55 kDa member of the Ig superfamily expressed mainly on activated T and B lymphocytes. Expression is induced on activated myeloid cells as well. CD279 (PD1) is thought to be involved in lymphocyte clonal selection and plays a key role in peripheral tolerance and autoimmune disease in mice. The ligands of CD279 (PD1), PD-L1 (B7-H1), and PD-L2 (B7-DC) belong to the B7 immunoglobulin superfamily. Clone HA2-7B1 has been used to block the binding of PD1 to its ligands.

Applications

The CD279 (PD1) pure – functional grade antibody can be used to block the binding of PD1 to its ligand PDL1 and PDL2.

Alternative Names

PDCD1, Ly101, PD1, Pdc1

Technical specifications

  • Antigen: CD279 (PD1)
  • Clone: HA2-7B1
  • Isotype: rat IgG2b
  • Alternative names of antigen: PDCD1, Ly101, PD1, Pdc1
  • Entrez Gene ID: 18566
  • Molecular mass of antigen [kDa]: 29
  • Distribution of antigen: B cells, monocytes, spleen, T cells, thymocytes
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

CD279 (PD1) pure - functional grade, mouse

  • HA2-7B1
  • For research use only
500 µg in 1 mL
130-094-944
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