CD276 antibodies, human

CD276 antibodies, human

Clone: FM276 | Dilution: 1:11
Clone FM276 reacts with human CD276 (B7-H3), a type I transmembrane protein expressed at low levels in human liver, lung, bladder, testis, prostate, breast, placenta, lymphoid organs, and many human cancers. Surface expression can be induced on T cells, natural killer cells, and macrophages as well as on dendritic cells (DC) by IFN-γ and on monocytes by granulocyte macrophage colony-stimulating factor (GM-CSF) and interleukin 4 (IL-4). B7-H3 has been shown to function as costimulatory molecule for T cell activation by inducing T cell proliferation and IFN-γ production.

Alternative Names

4Ig-B7-H3, B7-H3, B7RP-2

Technical specifications

  • Antigen: CD276
  • Clone: FM276
  • Isotype: mouse IgG2bκ
  • Isotype control: Mouse IgG2b – isotype control antibodies
  • Alternative names of antigen: 4Ig-B7-H3, B7-H3, B7RP-2
  • Entrez Gene ID: 80381
  • Molecular mass of antigen [kDa]: 54
  • Distribution of antigen: B cells, dendritic cells, epithelial cells, heart, liver, monocytes, NK cells, pancreas, placenta, small intestine, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, Biotin
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