CD271 (LNGFR) antibodies, human

CD271 (LNGFR) antibodies, human

Clone: REA844 | Dilution: 1:50
Clone REA844 recognizes the human CD271 antigen, also known as low-affinity nerve growth factor receptor (LNGFR) or p75 neurotrophin receptor (NTR). CD271 belongs to the low-affinity neurotrophin receptors and the tumor necrosis factor receptor superfamily. Initially the human CD271 (LNGFR) was described to be expressed on cells of the central and peripheral nervous system and was suggested to be involved in the development, survival, and differentiation of cells.
Expression of CD271 (LNGFR) is found on mesenchymal stem/stromal cells (MSCs), follicular dendritic cells, mesenchymal cells involved in mesenchymal-epithelial interactions, autonomic and sensory neurons, oligodendrocytes, astrocytes, schwann cells, and neural crest stem cells.
Additional information: Clone REA844 displays negligible binding to Fc receptors.

Alternative Names

NGFR, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR, p75NGFR, NGFR (p75)

Technical specifications

  • Antigen: CD271 (LNGFR)
  • Clone: REA844
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: NGFR, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR, p75NGFR, NGFR (p75)
  • Entrez Gene ID: 4804
  • Molecular mass of antigen [kDa]: 43
  • Cross-reactivity: monkey, sheep, cat, dog, pig, rabbit
  • Distribution of antigen: mesenchymal stem cells, dendritic cells, epithelial cells, oligodendrocytes, astrocytes, Schwann cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515, Biotin
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