CD271 (LNGFR) antibodies, human

CD271 (LNGFR) antibodies, human

Clone: ME20.4-1.H4 | Dilution: 1:50
Clone ME20.4-1.H4 recognizes the CD271 antigen, also known as low-affinity nerve growth factor receptor (LNGFR) or neurotrophin receptor (p75 NTR). CD271 belongs to the low-affinity neurotrophin receptors and the tumor necrosis factor receptor superfamily. Initially the human CD271 (LNGFR) was described to be expressed on cells of the central and peripheral nervous system, and was suggested to be involved in the development, survival, and differentiation of cells.
CD271 (LNGFR) is expressed on
  • Mesenchymal stem/stromal cells (MSCs)2,3,4
  • Follicular dendritic cells5
  • Mesenchymal cells involved in mesenchymal-epithelial interactions6
  • Autonomic and sensory Neurons7
  • Oligodendrocytes8
  • Astrocytes9
  • Schwann cells10,11
  • Neural crest stem cells12

Alternative Names

NGFR, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR, p75NGFR, NGFR (p75)

Technical specifications

  • Antigen: CD271 (LNGFR)
  • Clone: ME20.4-1.H4
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: NGFR, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR, p75NGFR, NGFR (p75)
  • Entrez Gene ID: 4804
  • Molecular mass of antigen [kDa]: 43
  • Cross-reactivity: monkey, goat, dog, pig, sheep
  • Distribution of antigen: B cells, bone marrow, cancer stem cells, dendritic cells, mesenchymal stem cells, monocytes, neurons
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, VioBright FITC, PE, APC, VioBlue, PE-Vio770, Biotin
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