CD271 (LNGFR) antibodies, human and mouse

CD271 (LNGFR) antibodies, human and mouse

Clone: REA648 | Dilution: 1:11
Clone REA648 recognizes the CD271 antigen, a type I transmembrane glycophosphoprotein, also known as low-affinity nerve growth factor receptor (LNGFR) or p75 neurotrophin receptor (p75 NTR). CD271 belongs to the low-affinity neurotrophin receptors and the tumor necrosis factor receptor superfamily. Initially the human CD271 was described to be expressed on cells of the central and peripheral nervous system, and was suggested to be involved in the development, survival, and differentiation of cells. Binding of neutrophins to the CD271 receptor initiates the stimulation of neuronal cells to survive and differentiate. CD271 is expressed on mesenchymal stem/stromal cells (MSCs), follicular dendritic cells, mesenchymal cells involved in mesenchymal-epithelial interactions, autonomic and sensory neurons, oligodendrocytes, astrocytes, schwann cells, and neural crest stem cells.
Additional information: Clone RE648 displays negligible binding to Fc receptors.

Alternative Names

NGFR (p75), p75NGFR, p75NTR, TNFRSF16, CD271, Gp80-LNGFR

Technical specifications

  • Antigen: CD271 (LNGFR)
  • Clone: REA648
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: NGFR (p75), p75NGFR, p75NTR, TNFRSF16, CD271, Gp80-LNGFR
  • Entrez Gene ID: 18053
  • Molecular mass of antigen [kDa]: 42
  • Cross-reactivity: guinea pig, rat,
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: stromal cells, mesenchymal stem cells, dendritic cells, oligodendrocytes, Schwann cells, neural stem cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE-Vio770, APC-Vio770, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD271 (LNGFR)-VioBright FITC, human and mouse

  • REA648
  • 1:11
  • For research use only
for 30
tests
(1)
130-110-115
-

CD271 (LNGFR)-VioBright FITC, human and mouse

  • REA648
  • 1:11
  • For research use only
for 100
tests
(1)
130-110-081
-

CD271 (LNGFR)-PE-Vio770, human and mouse

  • REA648
  • 1:11
  • For research use only
for 30
tests
(1)
130-110-113
-

CD271 (LNGFR)-PE-Vio770, human and mouse

  • REA648
  • 1:11
  • For research use only
for 100
tests
(1)
130-110-079
-

CD271 (LNGFR)-APC-Vio770, human and mouse

  • REA648
  • 1:11
  • For research use only
for 30
tests
(1)
130-110-114
-

CD271 (LNGFR)-APC-Vio770, human and mouse

  • REA648
  • 1:11
  • For research use only
for 100
tests
(1)
130-110-080
-

CD271 (LNGFR)-Biotin, human and mouse

  • REA648
  • 1:11
  • For research use only
for 30
tests
(1)
130-110-110
-

CD271 (LNGFR)-Biotin, human and mouse

  • REA648
  • 1:11
  • For research use only
for 100
tests
(1)
130-110-076
-

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