CD268 antibodies, mouse

CD268 antibodies, mouse

Clone: 7H22-E16 | Dilution: 1:10
Clone 7H22-E16 reacts with CD268, also known as B cell activation factor receptor (BAFF-R), a type III transmembrane TNF receptor family member. CD268 is expressed at high levels on resting B cells, at lower levels on activated B cells, and on a small subset of activated/memory T cells. BAFF, also known as BLys, mediates costimulatory responses in peripheral B and T cells. BAFF is a key regulator for B cell differentiation as well as survival and activation of peripheral B cell populations. Accordingly, CD268 appears to be particularly involved in the regulation of normal B cell survival and maturation, but also in the pathophysiology of aggressive B cell malignancies and autoimmune diseases.

Alternative Names

TNFRSF13c, BR3, BAFFR, Bcmd, Bcmd-1, Lvis22

Technical specifications

  • Antigen: CD268
  • Clone: 7H22-E16
  • Isotype: rat IgG1κ
  • Isotype control: Rat IgG1 – isotype control antibodies
  • Alternative names of antigen: TNFRSF13c, BR3, BAFFR, Bcmd, Bcmd-1, Lvis22
  • Entrez Gene ID: 72049
  • Molecular mass of antigen [kDa]: 19
  • Distribution of antigen: B cells, leukocytes, lymphocytes, spleen, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, Biotin
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