CD253 antibodies, mouse

CD253 antibodies, mouse

Clone: REA1030 | Dilution: 1:50
Clone REA1030 recognizes the mouse CD253 antigen, a type 2 transmembrane protein also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR).
Additional information: Clone REA1030 displays negligible binding to Fc receptors.

Alternative Names

TNFSF10, APO2L, Ly81, TL2, TRAIL

Technical specifications

  • Antigen: CD253
  • Clone: REA1030
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TNFSF10, APO2L, Ly81, TL2, TRAIL
  • Entrez Gene ID: 22035
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: B cells, dendritic cells, monocytes, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected References

    1. Wiley, S. R. et al. (1995) Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3(6): 673-682
    2. Hofmann, K. (1999) The modular nature of apoptotic signaling proteins. Cell. Mol. Life Sci. 55(8-9): 1113-1128
    3. Locksley, R. M. et al. (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104(4): 487-501
Product options: 17
130-117-559

CD253-FITC, mouse

30 µg in 200 µL (1)
-
130-117-560

CD253-PE, mouse

30 µg in 200 µL (1)
-
130-117-411

CD253-PE, mouse

150 µg in 1 mL (1)
-
130-117-561

CD253-APC, mouse

30 µg in 200 µL (1)
-
130-117-412

CD253-APC, mouse

150 µg in 1 mL (1)
-
130-117-562

CD253-VioBlue, mouse

30 µg in 200 µL (1)
-
130-117-413

CD253-VioBlue, mouse

150 µg in 1 mL (1)
-
130-117-563

CD253-PE-Vio615, mouse

30 µg in 200 µL (1)
-
130-117-414

CD253-PE-Vio615, mouse

150 µg in 1 mL (1)
-
130-117-564

CD253-PE-Vio770, mouse

30 µg in 200 µL (1)
-
130-117-415

CD253-PE-Vio770, mouse

150 µg in 1 mL (1)
-
130-117-565

CD253-APC-Vio770, mouse

30 µg in 200 µL (1)
-
130-117-566

CD253-PerCP-Vio700, mouse

30 µg in 200 µL (1)
-
130-117-567

CD253-VioBright 515, mouse

30 µg in 200 µL (1)
-
130-117-418

CD253-VioBright 515, mouse

150 µg in 1 mL (1)
-
130-117-568

CD253-Biotin, mouse

30 µg in 200 µL (1)
-
130-117-419

CD253-Biotin, mouse

150 µg in 1 mL (1)
-