CD223 antibodies – functional grade, mouse

CD223 antibodies – functional grade, mouse

Clone: C9B7W
Clone C9B7W recognizes an epitope within the D2 domain of murine CD233, also known as LAG-3, which is a 70 kDa high affinity MHC class II ligand. It is expressed on activated CD4
+
and CD8
+
α/β T cells and on a subset of NK cells. It has been reported that in association with the CD3 complex CD223 is a negative regulatory molecule to inhibit TCR-mediated signaling and to regulate homeostatic T cell expansion.

Applications

This pure – functional grade antibody is suited for cell culture functional assays, for example, blocking of receptor-ligand binding.

Alternative Names

LAG-3, Ly66

Technical specifications

  • Antigen: CD223
  • Clone: C9B7W
  • Isotype: rat IgG1
  • Alternative names of antigen: LAG-3, Ly66
  • Entrez Gene ID: 16768
  • Molecular mass of antigen [kDa]: 55
  • Distribution of antigen: NK cells, T cells
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

CD223 pure - functional grade, mouse

  • C9B7W
  • For research use only
0.5 mg in 0.5 mL
130-097-807
-

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