CD213α2 (IL-13Rα2) antibodies, human

CD213α2 (IL-13Rα2) antibodies, human

Clone: REA308 | Dilution: 1:11
Clone REA308 recognizes the human CD213α2 antigen, a single-pass type I membrane protein which is also known as interleukin-13 receptor subunit α-2 (IL-13Rα2). CD213α2 is a high affinity receptor for IL-13 that is used only by IL-13 and is quite distinct from CD213α1 (IL-13Rα1) that IL-13 shares with IL-4. CD213α2 is expressed by fibroblasts, smooth muscle cells, keratinocytes, and activated B cells. It has been thought to be a decoy receptor due to its short cytoplasmic tail and it exists on the cell membrane, intracellularly, and in soluble form. Recent reports revealed that membrane CD213α2 may have some signaling capabilities, and soluble CD213α2 is a critical endogenous modulator for IL-13 responses. Additionally, IL-13 signaling via CD213α2 plays a role in tumor immune surveillance.
Additional information: Clone REA308 displays negligible binding to Fc receptors.

Alternative Names

IL13RA2, CD213A2, CT19, IL-13R, IL13BP

Technical specifications

  • Antigen: CD213α2 (IL-13Rα2)
  • Clone: REA308
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: IL13RA2, CD213A2, CT19, IL-13R, IL13BP
  • Entrez Gene ID: 3598
  • Molecular mass of antigen [kDa]: 42
  • Distribution of antigen: B cells, fibroblasts, keratinocytes, smooth muscle
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
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