CD21 antibodies, human

CD21 antibodies, human

Clone: HB5
Clone HB5 recognizes CD21, a type I membrane glycoprotein. Expression of CD21 in humans is found on B cells, follicular dendritic cells, subsets of epithelial cells, and thymic T cells. The primary function attributed to CD21 has been to amplify the B cell receptor (BCR)–mediated signal transduction in response to antigen recognition. To enhance the BCR mediated activation, CD21 associates with CD19 and CD81 in a B cell–specific signal transduction complex, where interaction of BCR with CR2/CD19 amplifies the signals. In addition, CD21 serves as a receptor for split products of complement protein C3, the gp350/220 viral coat protein of the EBV, and the immunoregulatory protein CD23.

Alternative Names

CR2, C3dR, CR, CVID7, SLEB9

Technical specifications

  • Antigen: CD21
  • Clone: HB5
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: CR2, C3dR, CR, CVID7, SLEB9
  • Cross-reactivity:
    common marmoset (
    Callithrix jacchus
    )
  • Distribution of antigen: B cells, dendritic cells, T cells
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

CD21 pure, human

  • HB5
  • For research use only
100 µg in 100 µL
130-108-034
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