CD207 (Langerin) antibodies, human

CD207 (Langerin) antibodies, human

Clone: REA770 | Dilution: 1:50
Clone REA770 recognizes the CD207 antigen, a 40 kDa glycosylated type II transmembrane C-type lectin receptor, and the standard marker for human and murine Langerhans cells (LCs). LCs are a subset of dendritic cells (DCs) that reside in epithelia; the best studied example of these antigen-presenting cells are LCs of the epidermis. CD207 is directly involved in antigen capture as well as endocytosis and induces the formation of typical Birbeck granules in immature DCs.
Additional information: Clone REA770 displays negligible binding to Fc receptors.

Alternative Names

CLEC4K, Langerin

Technical specifications

  • Antigen: CD207 (Langerin)
  • Clone: REA770
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CLEC4K, Langerin
  • Entrez Gene ID: 50489
  • Molecular mass of antigen [kDa]: 37
  • Distribution of antigen: Langerhans cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515, Biotin
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