CD200 antibodies, rat

CD200 antibodies, rat

Clone: REA532 | Dilution: 1:10
Clone REA532 recognizes the rat CD200 antigen, which is a transmembrane glycoprotein containing two extracellular immunoglobulin domains and lacks intracellular signaling motifs or docking sites for adapter signaling molecules. CD200, also known as MRC OX-2 antigen, is expressed on a variety of tissues, including the nervous system, activated T cells, B cells, dendritic cells in lymphatic follicles, cells of glomeruli and ovarian degenerating follicles, and vascular endothelium. It is also distributed at the epithelium-derived tissues such as the thymus, retinas, and hair follicles. CD200 interacts with CD200R, an immunoglobulin superfamily inhibitory receptor expressed primarily on myeloid/monocyte lineage cells, and has a suppressive effect on T cell–mediated immune response.
Additional information: Clone REA532 displays negligible binding to Fc receptors.

Alternative Names

Cspmo2, MRCOX2, Mox2

Technical specifications

  • Antigen: CD200
  • Clone: REA532
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Cspmo2, MRCOX2, Mox2
  • Entrez Gene ID: 24560
  • Molecular mass of antigen [kDa]: 28
  • Distribution of antigen: T cells, B cells, dendritic cells, ovary, endothelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
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