CD2 antibodies – functional grade, mouse

CD2 antibodies – functional grade, mouse

Clone: RM2-5
The monoclonal antibody RM2-5 recognizes the type I transmembrane glycoprotein CD2, also known as LFA-2 or Ly-37. In mouse, CD2 is expressed on all lymphocytes except a subpopulation of intraepithelial T lymphocytes. It is a major receptor for CD48 and is involved in activation and differentiation of T cells. CD2-mediated cell-cell adhesion can be blocked by the RM2-5 antibody.

Applications

The CD2 pure – functional grade antibody is suited for functional assays, for example, blocking of CD2-mediated cell-cell adhesion.

Alternative Names

LFA-2, Ly-37

Technical specifications

  • Antigen: CD2
  • Clone: RM2-5
  • Isotype: rat IgG2bλ
  • Alternative names of antigen: LFA-2, Ly-37
  • Entrez Gene ID: 12481
  • Molecular mass of antigen [kDa]: 36
  • Distribution of antigen: B cells, T cells
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
  • Selected References

    1. Nakamura, T. et al. (1990) Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions. J. Immunol. 145: 3628-3634
    2. Yagita, H. et al. (1989) Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells. Proc. Natl. Acad. Sci. U.S.A. 86: 645-649
    3. Davis, S. J. and van der Merwe, P. A. (1996) The structure and ligand interactions of CD2: implications for T-cell function. Immunol. Today 17(4): 177-187
Product options: 1

Product information

Size
Order no.
Price

CD2 pure - functional grade, mouse

  • RM2-5
  • For research use only
500 µg in 0.5 mL
130-100-617
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