CD1a antibodies, human

CD1a antibodies, human

Clone: REA736 | Dilution: 1:50
Clone REA736 recognizes the human CD1a antigen, a 40 kDa type I membrane glycoprotein, also known as T6 or Leu-6, which is a member of the immunglobulin superfamily. It shares functional and structural similarities with MHC I class molecules and is associated with β2-microglobulin. CD1a plays a role in antigen presentation by binding lipid and glycolipid antigens and presenting them to T cell receptors on natural killer T cells. CD1a is expressed on Langerhans cells, dendritic cells, and cortical thymocytes.
Additional information: Clone REA736 displays negligible binding to Fc receptors

Alternative names

HTA1, CD1, FCB6, R4, T6, Leu-6

Technical specifications

  • Antigen: CD1a
  • Clone: REA736
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HTA1, CD1, FCB6, R4, T6, Leu-6
  • Entrez Gene ID: 909
  • Molecular mass of antigen [kDa]: 35
  • Distribution of antigen: B cells, dendritic cells, Langerhans cells, lymphocytes, macrophages, monocytes, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Hanau, D. et al. (1990) Possible mechanism of action of CD1a antigens. J. Invest. Dermatol. 95(5): 503-505
    2. Calabi, F. et al. (1991) The CD1 system. Tissue Antigens 37(1): 1-9
    3. Blumberg, R. S. et al. (1995) Structure and function of the CD1 family of MHC-like cell surface proteins. Immunol. Rev. 147: 5-29
Product options: 16
130-112-021

CD1a-FITC, human

for 30
tests
(1)
-
130-111-869

CD1a-FITC, human

for 100
tests
(1)
-
130-112-022

CD1a-PE, human

for 30
tests
(1)
-
130-111-870

CD1a-PE, human

for 100
tests
(1)
-
130-112-023

CD1a-APC, human

for 30
tests
(1)
-
130-111-871

CD1a-APC, human

for 100
tests
(1)
-
130-112-027

CD1a-VioBlue, human

for 30
tests
(1)
-
130-111-875

CD1a-VioBlue, human

for 100
tests
(1)
-
130-112-024

CD1a-PE-Vio770, human

for 30
tests
(1)
-
130-111-872

CD1a-PE-Vio770, human

for 100
tests
(1)
-
130-112-025

CD1a-APC-Vio770, human

for 30
tests
(1)
-
130-111-873

CD1a-APC-Vio770, human

for 100
tests
(1)
-
130-112-026

CD1a-PerCP-Vio700, human

for 30
tests
(1)
-
130-111-874

CD1a-PerCP-Vio700, human

for 100
tests
(1)
-
130-112-020

CD1a-Biotin, human

for 30
tests
(1)
-
130-111-868

CD1a-Biotin, human

for 100
tests
(1)
-