CD197 (CCR7) antibodies, mouse

CD197 (CCR7) antibodies, mouse

Clone: 4B12 | Dilution: 1:10
Clone 4B12 reacts with CD197 (CCR7), a chemokine receptor for chemokines CCL19 and CCL21. CD197, like other chemokine receptors, has seven-transmembrane spanning domains and signals via G proteins. Expression of CD197 is found on semi-mature and mature dendritic cells (DCs), naive B and T cells, regulatory T (Treg) cells, a subpopulation of T cells called central memory T cells, and non-immune malignant cells. CD197 is involved in regulating homing of immune cells, immunity to pathogens, immune tolerance, development and function of Tregs, and manifestation of autoimmunity.

Alternative Names

CCR7, CC-CKR-7, CCR-7, Cdw197, CMKBR7, EBI1, Ebi1h

Technical specifications

  • Antigen: CD197 (CCR7)
  • Clone: 4B12
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: CCR7, CC-CKR-7, CCR-7, Cdw197, CMKBR7, EBI1, Ebi1h
  • Entrez Gene ID: 12775
  • Molecular mass of antigen [kDa]: 40
  • Distribution of antigen: T cells, B cells, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
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