CD197 (CCR7) antibodies, human

CD197 (CCR7) antibodies, human

Clone: FR 11-11E8 | Dilution: 1:11
CD197, also known as chemokine (C-C motif) receptor 7 (CCR7), is a chemokine receptor with a C-C motif that mediates homing of T cells to secondary lymphoid organs via high endothelial venules (HEV). For example, naive T cells migrate very efficiently through lymph nodes using the adhesion molecules L-selectin, CD62L, and CCR7. Ligands for CCR7, e.g. CCL19, are expressed by the HEV of secondary lymphoid organs, by parenchymal cells within T cell zones of lymph nodes, and by endothelial cells at the openings of lymphatic vessels within peripheral tissues. Expression of CCR7 and the CD45RA isoform distinguishes three subsets of T cells: naive T cells (CCR7
+
CD45RA
+
), central memory T cells (CCR7
+
CD45RA
), and effector memory T cells (CCR7
CD45RA
).

Alternative Names

CCR7, BLR-2, CC-CKR-7, CCR-7, Cdw197, CMKBR7, EBI-1

Technical specifications

  • Antigen: CD197 (CCR7)
  • Clone: FR 11-11E8
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CCR7, BLR-2, CC-CKR-7, CCR-7, Cdw197, CMKBR7, EBI-1
  • Entrez Gene ID: 1236
  • Molecular mass of antigen [kDa]: 40
  • Distribution of antigen: B cells, dendritic cells, macrophages, NK cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, pure
Product options: 4

Product information

Size
Order no.
Price

CD197 (CCR7)-PE, human

  • FR 11-11E8
  • 1:11
  • For research use only
for 30
tests
(1)
130-098-124
-

CD197 (CCR7)-PE, human

  • FR 11-11E8
  • 1:11
  • For research use only
for 100
tests
(1)
130-093-621
-

CD197 (CCR7)-APC, human

  • FR 11-11E8
  • 1:11
  • For research use only
for 30
tests
(1)
130-098-125
-

CD197 (CCR7) pure, human

  • FR 11-11E8
  • For research use only
100 µg in 1 mL
130-093-626
-

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