CD185 (CXCR5) antibodies, mouse

CD185 (CXCR5) antibodies, mouse

Clone: REA215 | Dilution: 1:10
Clone REA215 recognizes murine CD185, which is a 42 kDa multipass chemokine receptor, also known as CXCR5 or burkitt lymphoma receptor-1 (BLR). Expression of CD185 is found on mature recirculating B cells, a small subset of CD4
+
and CD8
+
T cells, and skin-derived migratory dendritic cells. CXCR5 recognizes B cell–attracting chemokine 1 (BCA-1)/ CXCL13 as ligand, which is a homeostatic chemokine, constitutively secreted by stromal cells in B cell areas of secondary lymphoid tissues (follicles). CXCR5 is involved in recruitment of circulating naive B cells to follicles and trafficking and homing of B1 B cells. Mice lacking CXCR5 gene display defective primary follicles and germinal centers formation in the spleen and Peyer patches, and lack inguinal lymph nodes.
Additional information: Clone REA215 displays negligible binding to Fc receptors.

Alternative Names

CXCR5, BLR1, CXC-R5, CXCR-5, Gpcr6, MDR15

Technical specifications

  • Antigen: CD185 (CXCR5)
  • Clone: REA215
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CXCR5, BLR1, CXC-R5, CXCR-5, Gpcr6, MDR15
  • Distribution of antigen: B cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, PE-Vio615, Biotin
Product options: 6

Product information

Size
Order no.
Price

CD185 (CXCR5)-PE, mouse

  • REA215
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-103-114
-

CD185 (CXCR5)-PE, mouse

  • REA215
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-288
-

CD185 (CXCR5)-PE-Vio615, mouse

  • REA215
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-107-656
-

CD185 (CXCR5)-PE-Vio615, mouse

  • REA215
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-107-612
-

CD185 (CXCR5)-Biotin, mouse

  • REA215
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-102-057
-

CD185 (CXCR5)-Biotin, mouse

  • REA215
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-101-873
-

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