CD185 (CXCR5) antibodies, human

CD185 (CXCR5) antibodies, human

Clone: REA103 | Dilution: 1:11
The monoclonal antibody REA103 recognizes human CD185 which is a 42 kDa G-protein–coupled chemokine receptor and is also known as CXCR5, monocyte-derived receptor 15 (MDR15), or Burkitt lymphoma receptor-1 (BLR1). BLR-1 was originally identified on cells of Burkitt´s lymphoma and B cells. B-cell attracting chemokine 1 (BCA-1), also known as B-lymphocyte chemoattractant (BLC) or CXCL13, is the ligand of CD185. It is further expressed on central memory CD4 T cells, T folicular helper cells, and on a migratory population of skin-derived dendritic cells.
Additional information: Clone REA103 displays negligible binding to Fc receptors.

Alternative Names

CXCR5, BLR1, MDR15

Technical specifications

  • Antigen: CD185 (CXCR5)
  • Clone: REA103
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CXCR5, BLR1, MDR15
  • Entrez Gene ID: 643
  • Molecular mass of antigen [kDa]: 42
  • Distribution of antigen: B cells, monocytes, neurons, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, APC, PE-Vio615, Biotin
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA103
RF8B2++
MU5UBEE++
J252D4++
51505++
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