CD184 (CXCR4) antibodies, mouse

CD184 (CXCR4) antibodies, mouse

Clone: REA107 | Dilution: 1:50
Clone REA107 reacts with CD184, a receptor for C-X-C chemokine CXCL12/SDF-1. CD184 is a seven membrane spanning receptor and belongs to the family of G-protein coupled chemokine receptors. Expression of CD184 is found in tissues including spleen, thymus, bone marrow, lymph nodes, and at lower levels in small intestine, kidney, and stomach. Diverse functions of CD184 include promoting survival and proliferation of hematopoietic stem cells, inducing apoptosis in T cells, regulating osteoclastogenesis, B cell development, vascularization of the gastrointestinal tract, germ cell migration/survival, and cerebellar development. CD184 also serves as a co-receptor for entry into target cells by HIV-1 X4 and interacts with extracellular ubiquitin.
Additional information: Clone REA107 displays negligible binding to Fc receptors.

Alternative Names

CXCR4, Cmkar4, LESTR, PB-CKR, PBSF/SDF-1, Sdf1r, b2b220Clo, Fusin, SDF-1 receptor

Technical specifications

  • Antigen: CD184 (CXCR4)
  • Clone: REA107
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CXCR4, Cmkar4, LESTR, PB-CKR, PBSF/SDF-1, Sdf1r, b2b220Clo, Fusin, SDF-1 receptor
  • Entrez Gene ID: 12767
  • Molecular mass of antigen [kDa]: 40
  • Distribution of antigen: B cells, T cells, hematopoietic stem cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE
Product options: 1

Product information

Order no.

CD184 (CXCR4)-PE, mouse

  • REA107
  • 1:50
  • For research use only
30 µg in 200 µL (1)

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