CD181 (CXCR1) antibodies, human

CD181 (CXCR1) antibodies, human

Clone: 8F1 | Dilution: 1:11
Clone 8F1 recognizes the human CD181 antigen, a multi-pass membrane protein also known as C-X-C chemokine receptor type 1 (CXCR1) or IL-8 receptor A (IL-8RA). CD181 is expressed as homodimer or heterodimer with CD182 (CXCR2) and found on granulocytes, NK cells, a subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. It is one of two high-affinity receptors for IL-8, a major mediator of immune and inflammatory responses implicated in many disorders, including tumor growth. IL-8, released in response to inflammatory stimuli, binds to the extracellular part of CD181. The ligand-activated intracellular signaling pathways results in neutrophil migration to the site of inflammation.

Alternative Names

CXCR1, C-C, C-C-CKR-1, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA

Technical specifications

  • Antigen: CD181 (CXCR1)
  • Clone: 8F1
  • Isotype: mouse IgG2bκ
  • Isotype control: Mouse IgG2b – isotype control antibodies
  • Alternative names of antigen: CXCR1, C-C, C-C-CKR-1, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA
  • Entrez Gene ID: 3577
  • Molecular mass of antigen [kDa]: 40
  • Distribution of antigen: granulocytes, NK cells, lymphocytes, mast cells, monocytes, endothelial cells, megakaryocytes, oligodendrocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700
Product options: 16

Product information

Size
Order no.
Price

CD181 (CXCR1)-FITC, human

  • 8F1
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-392
-

CD181 (CXCR1)-FITC, human

  • 8F1
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-351
-

CD181 (CXCR1)-PE, human

  • 8F1
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-393
-

CD181 (CXCR1)-PE, human

  • 8F1
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-352
-

CD181 (CXCR1)-APC, human

  • 8F1
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-394
-

CD181 (CXCR1)-APC, human

  • 8F1
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-353
-

CD181 (CXCR1)-VioBlue, human

  • 8F1
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-391
-

CD181 (CXCR1)-VioBlue, human

  • 8F1
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-350
-

CD181 (CXCR1)-VioGreen, human

  • 8F1
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-390
-

CD181 (CXCR1)-VioGreen, human

  • 8F1
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-349
-

CD181 (CXCR1)-PE-Vio770, human

  • 8F1
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-395
-

CD181 (CXCR1)-PE-Vio770, human

  • 8F1
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-354
-

CD181 (CXCR1)-APC-Vio770, human

  • 8F1
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-396
-

CD181 (CXCR1)-APC-Vio770, human

  • 8F1
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-355
-

CD181 (CXCR1)-PerCP-Vio700, human

  • 8F1
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-397
-

CD181 (CXCR1)-PerCP-Vio700, human

  • 8F1
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-356
-

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