CD18 antibodies, human

Clone: TS1/18 | Dilution: 1:50
Clone TS1/18 reacts with CD18, a type I transmembrane protein with an approximate molecular weight of 90–95 kDa. It non-covalently associates with α subunits CD11a (αL), CD11b (αM), CD11c (αX), and CD11d (αD) to form functional integrins which are expressed on leucocytes. CD18 associated integrins bind several ligands including cell surface and extracellular matrix proteins and are involved in cell-cell and cell-extracellular matrix interactions, immune regulation, and immune tolerance. Leucocytes of patients lacking CD18 or expressing dysfunctional CD18 are defective in chemotaxis, phagocytosis, and homotypic aggregation.

Alternative Names

ITGB2, CD18, LAD, LCAMB, LFA-1, Mac-1 α, MF17, MFI7

Technical specifications

  • Antigen: CD18
  • Clone: TS1/18
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: ITGB2, CD18, LAD, LCAMB, LFA-1, Mac-1 α, MF17, MFI7
  • Cross-reactivity: porcine
  • Distribution of antigen: leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE

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