CD178 antibodies – functional grade, mouse

CD178 antibodies – functional grade, mouse

Clone: MFL3
The monoclonal antibody MFL3 recognizes the type II transmembrane glycoprotein mouse CD178, also known as Fas Ligand (FasL) or CD95 Ligand (CD95L), which is a 40 kDa member of the TNF cytokine family expressed on activated lymphocytes such as T cells, NK cells, or monocytes as well as in immune-privilaged sites, e.g cornea or testis. CD178 can trigger apoptosis through trimerization of the Fas receptor CD95. Thereby, CD178 and CD95 play a key role in the regulation of the immune system. Cleavage of membrane bound CD178 from the cell surface via matrix metalloproteinases (such as MMP-7) generates soluble CD178 molecules.

Applications

This pure – functional grade antibody is suited for cell culture functional assays, for example, blocking of receptor-ligand binding.

Alternative Names

FasL, APT1LG1, CD95L, TNFSF6, gld

Technical specifications

  • Antigen: CD178
  • Clone: MFL3
  • Isotype: hamster IgG
  • Alternative names of antigen: FasL, APT1LG1, CD95L, TNFSF6, gld
  • Distribution of antigen: T cells, monocytes, NK cells
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1

Product information

Size
Order no.
Price

CD178 pure - functional grade, mouse

  • MFL3
  • For research use only
500 µg in 0.5 mL
130-101-198
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