CD163 antibodies, human

CD163 antibodies, human

Clone: GHI/61.1 | Dilution: 1:11
The monoclonal antibody GHI/61.1 reacts with human CD163, a single-chain transmembrane protein also known as hemoglobin scavenger receptor or M130. It is expressed by mature tissue macrophages and peripheral blood monocytes. The expression of CD163 is up-regulated
in vitro
and
in vivo
by anti-inflammatory mediators such as IL-10 and (gluco)corticosteroid and is shed to blood upon inflammatory activation of macrophages. CD163 functions as a high affinity scavenger receptor for the complex of haemoglobin and haptoglobin. Depending on the ligand, crosslinking of M130 initiates signal transduction leading to the production of proinflammatory cytokines Il-1ß, IL-6, and GM-CSF or the antiinflammatory cytokine IL-10.

Alternative Names

GHI/61, M130, MM130, CD163

Technical specifications

  • Antigen: CD163
  • Clone: GHI/61.1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: GHI/61, M130, MM130, CD163
  • Entrez Gene ID: 9332
  • Molecular mass of antigen [kDa]: 121
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: bone marrow, CNS cells, liver, macrophages, monocytes, spleen, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, Biotin
Product options: 10

Product information

Size
Order no.
Price

CD163-FITC, human

  • GHI/61.1
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-969
-

CD163-FITC, human

  • GHI/61.1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-626
-

CD163-PE, human

  • GHI/61.1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-628
-

CD163-APC, human

  • GHI/61.1
  • 1:11
  • For research use only
for 30
tests
(1)
130-100-612
-

CD163-APC, human

  • GHI/61.1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-630
-

CD163-VioBlue, human

  • GHI/61.1
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-973
-

CD163-VioBlue, human

  • GHI/61.1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-624
-

CD163-PE-Vio770, human

  • GHI/61.1
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-546
-

CD163-PE-Vio770, human

  • GHI/61.1
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-484
-

CD163-Biotin, human

  • GHI/61.1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-622
-

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