CD161 antibodies, rat

CD161 antibodies, rat

Clone: REA227 | Dilution: 1:10
Clone REA227 recognizes rat CD161, a C-type lectin membrane glycoprotein also known as NKR-P1. CD161 is expressed as an 80 kDa disulphide-linked homodimer and is found on most NK cells, T cell subsets, and many dendritic cells. In peripheral blood, CD161 is preferentially expressed on T cells of memory phenotype, but it can also be found on subsets of thymocytes and fetal liver T cells. CD161 has been implicated in triggering NK-mediated cytotoxicity, contributing to target cell recognition by NK cells.
Additional information: Clone REA227 displays negligible binding to Fc receptors.

Alternative Names

NK1.1, NKR-P1C, Ly-55

Technical specifications

  • Antigen: CD161
  • Clone: REA227
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: NK1.1, NKR-P1C, Ly-55
  • Entrez Gene ID: 25192, 362443, 678513, 689817, 683758
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: NK cells, granulocytes, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770
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