CD158e (KIR3DL1) antibodies, human

CD158e (KIR3DL1) antibodies, human

Clone: DX9 | Dilution: 1:11
Clone DX9 recognizes CD158e (KIR3DL1), a member of the killer immunoglobulin-like receptor (KIR) family expressed on CD56
dim
CD16
+
natural killer (NK) cells and CD8
+
T cells. KIRs contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be further subdivided into inhibitory KIRs and activating KIRs (KIR2DS or KIR3DS). KIR3DL1 provides an inhibitory signal of NK cell lytic activity upon interaction with its specific ligand, HLA-Bw4.

Alternative Names

KIR3DL1, NKB1, NKB1B, p70

Technical specifications

  • Antigen: CD158e (KIR3DL1)
  • Clone: DX9
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: KIR3DL1, NKB1, NKB1B, p70
  • Entrez Gene ID: 3811
  • Molecular mass of antigen [kDa]: 47
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PerCP, PE-Vio770, Biotin, pure
  • Selected References

    1. Farag, S. S. et al. (2002) Natural killer cell receptors: new biology and insights into the graft-versus-leukaemia effect. Blood 100(6): 1935-1947
    2. Djeu, J. et al. (2002) A view to a kill: signals triggering cytotoxicity. Clin. Cancer Res. 8: 636-640
    3. Hsu, K. et al. (2002) The killer cell immunoglobin-like (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol. Rev. 190: 40-52
    4. Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196
Product options: 14
130-099-387

CD158e (KIR3DL1)-FITC, human

for 30
tests
(1)
-
130-092-568

CD158e (KIR3DL1)-FITC, human

for 100
tests
(1)
-
130-092-473

CD158e (KIR3DL1)-PE, human

for 100
tests
(1)
-
130-099-839

CD158e (KIR3DL1)-APC, human

for 30
tests
(1)
-
130-092-474

CD158e (KIR3DL1)-APC, human

for 100
tests
(1)
-
130-099-693

CD158e (KIR3DL1)-VioBlue, human

for 30
tests
(1)
-
130-095-234

CD158e (KIR3DL1)-VioBlue, human

for 100
tests
(1)
-
130-108-374

CD158e (KIR3DL1)-VioGreen, human

for 30
tests
-
130-108-343

CD158e (KIR3DL1)-VioGreen, human

for 100
tests
-
130-095-287

CD158e (KIR3DL1)-PerCP, human

for 100
tests
(1)
-
130-099-960

CD158e (KIR3DL1)-PE-Vio770, human

for 30
tests
(1)
-
130-099-959

CD158e (KIR3DL1)-PE-Vio770, human

for 100
tests
(1)
-
130-092-475

CD158e (KIR3DL1)-Biotin, human

for 100
tests
(1)
-
130-092-555

CD158e (KIR3DL1) pure, human

100 µg in 1 mL
-