CD158b2 (KIR2DL3) antibodies, human

CD158b2 (KIR2DL3) antibodies, human

Clone: REA147 | Dilution: 1:11
Clone REA147 recognizes CD158b2, a killer cell immunoglobulin-like inhibitory receptor (KIR). Expressed by natural killer (NK) cells and a subset of T cells, KIR family of receptors are transmembrane glycoproteins and interact with MHC class I molecules. This interaction allows the KIR receptors to modulate the killing function of cells bearing them. The KIR proteins are categorized by the number of extracellular immunoglobulin domains (2D or 3D) and by the length (long (L) or short (S)) of the cytoplasmic domain. KIR proteins with the long cytoplasmic domain, such as CD158b2, transduce inhibitory signals via an immune tyrosine-based inhibitory motif (ITIM).
Additional information: Clone REA147 displays negligible binding to Fc receptors.

Alternative names

KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3

Technical specifications

  • Antigen: CD158b2 (KIR2DL3)
  • Clone: REA147
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3
  • Entrez Gene ID: 3804
  • Molecular mass of antigen [kDa]: 36
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Gendzekhadze, K. et al. (2009) Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands. Proc. Natl. Acad. Sci. U.S.A. 106: 18692-18697
    2. Keaney, L. et al. (2004) Investigation of killer cell immunoglobulin-like receptor gene diversity III. KIR2DL3. Tissue Antigens 64(2): 188-194
Product options: 12
130-100-124

CD158b2 (KIR2DL3)-FITC, human

for 30
tests
(1)
-
130-100-125

CD158b2 (KIR2DL3)-FITC, human

for 100
tests
(1)
-
130-100-122

CD158b2 (KIR2DL3)-PE, human

for 30
tests
(1)
-
130-100-121

CD158b2 (KIR2DL3)-PE, human

for 100
tests
(1)
-
130-100-130

CD158b2 (KIR2DL3)-APC, human

for 30
tests
(1)
-
130-100-131

CD158b2 (KIR2DL3)-APC, human

for 100
tests
(1)
-
130-100-222

CD158b2 (KIR2DL3)-PE-Vio770, human

for 30
tests
(1)
-
130-100-117

CD158b2 (KIR2DL3)-PE-Vio770, human

for 100
tests
(1)
-
130-100-120

CD158b2 (KIR2DL3)-PerCP-Vio700, human

for 30
tests
(1)
-
130-100-118

CD158b2 (KIR2DL3)-PerCP-Vio700, human

for 100
tests
(1)
-
130-100-126

CD158b2 (KIR2DL3)-Biotin, human

for 30
tests
(1)
-
130-100-127

CD158b2 (KIR2DL3)-Biotin, human

for 100
tests
(1)
-