CD158b2 (KIR2DL3) antibodies, human

CD158b2 (KIR2DL3) antibodies, human

Clone: REA147 | Dilution: 1:11
Clone REA147 recognizes CD158b2, a killer-cell immunoglobulin-like inhibitory receptor (KIR). Expressed by natural killer and a subset of T cells, KIR family of receptors are transmembrane glycoproteins and interact with MHC class I molecules. This interaction allows the KIR receptors to modulate the killing function of cells bearing them. The KIR proteins are categorized by the number of extracellular immunoglobulin domains (2D or 3D) and by the length (long (L) or short (S)) of the cytoplasmic domain. KIR proteins with the long cytoplasmic domain, such as CD158b2, transduce inhibitory signals via an immune tyrosine-based inhibitory motif (ITIM).
Additional information: Clone REA147 displays negligible binding to Fc receptors.

Alternative Names

KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3

Technical specifications

  • Antigen: CD158b2 (KIR2DL3)
  • Clone: REA147
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3
  • Entrez Gene ID: 3804
  • Molecular mass of antigen [kDa]: 36
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, PerCP-Vio700, Biotin
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