CD156c (ADAM10) antibodies, human

CD156c (ADAM10) antibodies, human

Clone: REA309 | Dilution: 1:11
Clone REA309 recognizes the human CD156c antigen, a single-pass type I membrane protein which is also known as disintegrin or metalloproteinase domain-containing protein 10 (ADAM10). CD156c belongs to the family of disintegrin and metalloproteinases (ADAMs) and is expressed ubiquitously on hematopoietic and non-hematopoietic cells. ADAMs have emerged as the major proteinase family that mediates proteolytic ectodomain release, a process known as shedding. This shedding process has been recognised as a key mechanism for regulating the function of a diversity of cell surface proteins. Dysregulation of ectodomain shedding is associated with autoimmune and cardiovascular diseases, neurodegeneration, infection, inflammation, and cancer. CD156c has been studied in the context of ectodomain shedding and has been demonstrated as key molecule in most of the shedding events in cancer and neurodegenerative disorders.
Additional information: Clone REA309 displays negligible binding to Fc receptors.

Alternative Names

ADAM10, AD10, AD18, HsT18717, MADM, RAK, kuz

Technical specifications

  • Antigen: CD156c (ADAM10)
  • Clone: REA309
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ADAM10, AD10, AD18, HsT18717, MADM, RAK, kuz
  • Entrez Gene ID: 102
  • Molecular mass of antigen [kDa]: 59
  • Distribution of antigen: ubiquitous
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD156c (ADAM10)-FITC, human

  • REA309
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-424
-

CD156c (ADAM10)-FITC, human

  • REA309
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-406
-

CD156c (ADAM10)-PE, human

  • REA309
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-425
-

CD156c (ADAM10)-PE, human

  • REA309
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-407
-

CD156c (ADAM10)-APC, human

  • REA309
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-426
-

CD156c (ADAM10)-APC, human

  • REA309
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-408
-

CD156c (ADAM10)-Biotin, human

  • REA309
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-423
-

CD156c (ADAM10)-Biotin, human

  • REA309
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-405
-

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