CD155 antibodies, human

Clone: PV404.19 | Dilution: 1:50
Clone PV404.19 recognizes the human CD155 antigen, a single-pass type I membrane protein also known as poliovirus receptor (PVR) or nectin-like protein 5 (NECL-5). CD155 is composed of two Ig-like C2-type domains and one Ig-like V-type domain that is necessary for poliovirus binding and uptake. Four different isotypes (α to δ) exist, originated from alternate splicing of the CD155 mRNA. CD155 is a broadly expressed receptor which is, e.g., found on monocytes, a T cell subset, and neurons of the central nervous system. CD155 is also expressed on some CD34
+
progenitor cells, particulary on progenitors committed in myeloid differentiation. It can interact with several ligands, such as CD226, TIGIT, CD96, vitronectin, integrin αvβ3, and PDGFR. The functions of CD155 include roles in cell adhesion, neural differentiation, and NK cell effector functions.

Alternative Names

PVR, HVED, NECL-5, PVS, TAGE4

Technical specifications

  • Antigen: CD155
  • Clone: PV404.19
  • Isotype: mouse IgG1
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: PVR, HVED, NECL-5, PVS, TAGE4
  • Entrez Gene ID: 5817
  • Molecular mass of antigen [kDa]: 43
  • Distribution of antigen: T cells, monocytes, neurons, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC

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