CD155 antibodies, human

CD155 antibodies, human

Clone: PV404.19 | Dilution: 1:11
Clone PV404.19 recognizes the human CD155 antigen, a single-pass type I membrane protein also known as poliovirus receptor (PVR) or nectin-like protein 5 (NECL-5). CD155 is composed of two Ig-like C2-type domains and one Ig-like V-type domain that is necessary for poliovirus binding and uptake. Four different isotypes (α to δ) exist, originated from alternate splicing of the CD155 mRNA. CD155 is a broadly expressed receptor which is, e.g., found on monocytes, a T cell subset, and neurons of the central nervous system. CD155 is also expressed on some CD34
+
progenitor cells, particulary on progenitors committed in myeloid differentiation. It can interact with several ligands, such as CD226, TIGIT, CD96, vitronectin, integrin αvβ3, and PDGFR. The functions of CD155 include roles in cell adhesion, neural differentiation, and NK cell effector functions.

Alternative names

PVR, HVED, NECL-5, PVS, TAGE4

Technical specifications

  • Antigen: CD155
  • Clone: PV404.19
  • Isotype: mouse IgG1
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: PVR, HVED, NECL-5, PVS, TAGE4
  • Entrez Gene ID: 5817
  • Molecular mass of antigen [kDa]: 43
  • Distribution of antigen: T cells, monocytes, neurons, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, Biotin
  • Selected references

    1. Lozano, E. et al. (2013) The CD226/CD155 interaction regulates the proinflammatory (Tʜ1/Tʜ17)/anti-inflammatory (Tʜ2) balance in humans. J. Immunol. 191(7): 3673-3680
    2. Mendelsohn, C. L. et al. (1989) Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily. Cell 56(5): 855-865
Product options: 6
130-105-905

CD155-PE, human

for 30
tests
(1)
-
130-105-846

CD155-PE, human

for 100
tests
(1)
-
130-105-906

CD155-APC, human

for 30
tests
(1)
-
130-105-847

CD155-APC, human

for 100
tests
(1)
-
130-111-936

CD155-Biotin, human

for 30
tests
(1)
-
130-111-772

CD155-Biotin, human

for 100
tests
(1)
-