CD152 antibodies, mouse

CD152 antibodies, mouse

Clone: UC10-4B9 | Dilution: 1:10
The monoclonal antibody UC10-4B9 reacts with CD152, also known as cytotoxic T lymphocyte antigen-4 (CTLA-4), which is a 33 kDa member of the immunoglobin superfamily and is expressed on activated T cells at a low level. CTLA-4 and CD28 have similarities concerning B7 family counter-receptors. While CD28 delivers a costimulary signal in T cell activation, CD152 restricts the progression of T cells to an activated state by inhibiting interleukin 2 (IL-2) secretion and cellular proliferation. A large proportion of CTLA-4 is intracellular localized. For a complete detection it may be necessary to assess intracellular staining in addition to surface expression of CD152.

Alternative Names

CTLA4, CTLA-4, Ly-56

Technical specifications

  • Antigen: CD152
  • Clone: UC10-4B9
  • Isotype: hamster IgG1
  • Alternative names of antigen: CTLA4, CTLA-4, Ly-56
  • Entrez Gene ID: 12477
  • Molecular mass of antigen [kDa]: 21
  • Distribution of antigen: B cells, lymphocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
Product options: 3

Product information

Size
Order no.
Price

CD152-PE, mouse

  • UC10-4B9
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-570
-

CD152-APC, mouse

  • UC10-4B9
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-518
-

CD152-Biotin, mouse

  • UC10-4B9
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-101-924
-

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