CD152 antibodies, human

CD152 antibodies, human

Clone: REA1003 | Dilution: 1:50
Clone REA1003 recognizes the human CD152, an integral membrane protein of the immunoglobin superfamily which is also called CTLA-4. CD152 is a negative regulator of T cell activation. It is transiently expressed on activated CD28
+
T cells and is a ligand for CD80 and CD86. CD4
+
FoxP3
+
regulatory T cells are reported to constitutively express CD152. CD152 may also be detected on B cells when cultured with activated T cells.
Additional information: Clone REA1003 displays negligible binding to Fc receptor.

Alternative Names

CTLA4, ALPS5, CD, CELIAC3, CTLA-4, GRD4, GSE, IDDM12

Technical specifications

  • Antigen: CD152
  • Clone: REA1003
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: CTLA4, ALPS5, CD, CELIAC3, CTLA-4, GRD4, GSE, IDDM12
  • Entrez Gene ID: 1493
  • Molecular mass of antigen [kDa]: 21
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: B cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Vio515, Vio667
Product options: -

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