CD151 antibodies, human

CD151 antibodies, human

Clone: REA265 | Dilution: 1:11
Clone REA265 recognizes the CD151 antigen, a 29 kDa cell surface glycoprotein, which is also known as platelet-endothelial tetraspan antigen 3 (PETA-3) or tetraspanin-24 (Tspan-24). Like other tetraspanin family members, CD151 contains four hydrophobic transmembrane domains, two short cytoplasmic tails, and one small and one large extracellular loop. CD151 is expressed by many different cell types such as platelets, immature hematopoietic cells, megakaryocytes, keratinocytes, epithelial cells, muscle cells, Schwann cells, vascular endothelium, as well as epithelial cells. It complexes with integrins and other transmembrane 4 superfamily proteins and is involved in cellular processes including cell adhesion and regulates integrin trafficking and function. CD151 enhances cell motility, invasion, and metastasis of tumor cells.
Additional information: Clone REA265 displays negligible binding to Fc receptors.

Alternative Names

GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24

Technical specifications

  • Antigen: CD151
  • Clone: REA265
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24
  • Entrez Gene ID: 977
  • Molecular mass of antigen [kDa]: 28
  • Distribution of antigen: epithelial cells, platelets, keratinocytes, Schwann cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
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