CD140a antibodies, mouse

CD140a antibodies, mouse

Clone: APA5 | Dilution: 1:10
Clone APA5 reacts with the transmembrane glycoprotein CD140a, the α chain of the platelet-derived growth factor receptor (PDGFR). The two isoforms of the receptor can form homodimers (α/α or β/β) or α/β heterodimers. Receptor dimerization and transphosphorylation at tyrosine residues activates the intracellular kinase activity. CD140a is broadly expressed in embryonic tissue, mostly in cells of mesodermal origin in adult tissue, and embryonic stem cell–derived cardiomyogenic cells. Expression of CD140a is associated with various malignancies.

Alternative Names

PDGFRA, Pdgfr-2, PDGF-Rα

Technical specifications

  • Antigen: CD140a
  • Clone: APA5
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: PDGFRA, Pdgfr-2, PDGF-Rα
  • Entrez Gene ID: 18595
  • Molecular mass of antigen [kDa]: 120
  • Distribution of antigen: bone marrow, epithelial cells, fibroblasts, mesenchymal stem cells, monocytes, myeloid cells, osteoblasts, red blood cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
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Product information

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