CD137L (4-1BBL) antibodies, mouse

CD137L (4-1BBL) antibodies, mouse

Clone: REA962 | Dilution: 1:50
Clone REA962 recognizes the mouse CD137L antigen, a single-pass type II membrane protein also known as 4-1BB ligand (4-1BBL) or tumor necrosis factor ligand superfamily member 9 (Tnfsf9). CD137L is expressed on activated antigen-presenting cells and plays an essential role in regulating adaptive immune responses. Its receptor, 4-1BB is an inducible co-stimulatory member of the tumor necrosis factor receptor family expressed on activated CD4 and CD8 T cells. 4-1BB can enhance both the proliferation and the survival of murine CD4 and CD8 T cells. Recent evidence in mouse models suggests that 4-1BB/CD137L interaction plays an important role in the memory CD8 T cell response to viruses.
Additional information: Clone REA962 displays negligible binding to Fc receptors.

Alternative Names

4-1BB ligand, 4-1BBL, TNFSF9

Technical specifications

  • Antigen: CD137L (4-1BBL)
  • Clone: REA962
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: 4-1BB ligand, 4-1BBL, TNFSF9
  • Entrez Gene ID: 21950
  • Molecular mass of antigen [kDa]: 34
  • Distribution of antigen: B cells, dendritic cells, fibroblasts, monocytes, macrophages, lymphocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, VioBright 515, Biotin
  • Selected References

    1. Goodwin, R. G. et al. (1993) Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor. Eur. J. Immunol. 23(10): 2631-2641
    2. Wang, C. et al. (2009) Immune regulation by 4-1BB and 4-1BBL: complexities and challenges. Immunol. Rev. 229(1): 192-215
    3. Ma, J. et al. (2013) The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation. Sci Signal 6(295): ra87
Product options: 13

Product information

Size
Order no.
Price

CD137L (4-1BBL)-FITC, mouse

  • REA962
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-085
-

CD137L (4-1BBL)-PE, mouse

  • REA962
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-086
-

CD137L (4-1BBL)-PE, mouse

  • REA962
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-011
-

CD137L (4-1BBL)-APC, mouse

  • REA962
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-087
-

CD137L (4-1BBL)-APC, mouse

  • REA962
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-012
-

CD137L (4-1BBL)-PE-Vio615, mouse

  • REA962
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-091
-

CD137L (4-1BBL)-PE-Vio615, mouse

  • REA962
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-016
-

CD137L (4-1BBL)-PE-Vio770, mouse

  • REA962
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-088
-

CD137L (4-1BBL)-PE-Vio770, mouse

  • REA962
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-013
-

CD137L (4-1BBL)-VioBright 515, mouse

  • REA962
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-090
-

CD137L (4-1BBL)-VioBright 515, mouse

  • REA962
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-015
-

CD137L (4-1BBL)-Biotin, mouse

  • REA962
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-084
-

CD137L (4-1BBL)-Biotin, mouse

  • REA962
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-009
-