CD137 antibodies, mouse

CD137 antibodies, mouse

Clone: REA936 | Dilution: 1:50
Clone REA936 recognizes the mouse CD137 antigen, a single-pass type I membrane protein also known as 4-1BB or TNFRSF9, which is a member of the TNFR superfamily. CD137 is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen-presenting cells delivers a bidirectional co-stimulatory signal. CD137 engagement is shown to be required for CD8
+
T cell survival and memory formation. CD137 is reported to have a strong antagonistic effect in
in vitro
functional assays.
Additional information: Clone REA936 displays negligible binding to Fc receptors.

Alternative Names

TNFRSF9, 4-1BB, CDw137, ILA, Ly63

Technical specifications

  • Antigen: CD137
  • Clone: REA936
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TNFRSF9, 4-1BB, CDw137, ILA, Ly63
  • Entrez Gene ID: 21942
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: B cells, epithelial cells, fibroblasts, dendritic cells, lymphocytes, macrophages, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, Biotin

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