CD137 antibodies, mouse

CD137 antibodies, mouse

Clone: 17B5-1H1 | Dilution: 1:50
Clone 17B5 reacts with mouse CD137, also known as 4-1BB or TNFRSF9, a member of the TNFR superfamily. It is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen presenting cells (APCs) delivers a bidirectional costimulatory signal. CD137 engagement is shown to be required for CD8
+
T cell survival and memory formation. The monoclonal antibody 17B5 is reported to have strong antagonistic effect in
in vitro
functional assays.

Alternative Names

TNFRSF9, 4-1BB, CDw137, ILA, Ly63

Technical specifications

  • Antigen: CD137
  • Clone: 17B5-1H1
  • Isotype: hamster IgG2
  • Isotype control: For the appropriate isotype control antibody, please refer to the tab Related items.
  • Alternative names of antigen: TNFRSF9, 4-1BB, CDw137, ILA, Ly63
  • Entrez Gene ID: 21942
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: B cells, dendritic cells, epithelial cells, fibroblasts, lymphocytes, macrophages, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE-Vio770
Product options: 1

Product information

Size
Order no.
Price

CD137-PE-Vio770, mouse

  • 17B5-1H1
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-532
-

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