CD137 antibodies, human

CD137 antibodies, human

Clone: 4B4-1 | Dilution: 1:50
This antibody recognizes the CD137 (4-1BB) antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily. CD137 is mainly expressed on activated CD4
+
and CD8
+
T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells.
As a costimulatory molecule it is involved in the activation and survival of CD4
+
or CD8
+
T cells, and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8
+
T cells, as it is not expressed on resting CD8
+
T cells and its expression is reliably induced after 24 hours of stimulation.

Alternative Names

TNFRSF9, 4-1BB, CDw137, ILA

Technical specifications

  • Antigen: CD137
  • Clone: 4B4-1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: TNFRSF9, 4-1BB, CDw137, ILA
  • Entrez Gene ID: 3604
  • Molecular mass of antigen [kDa]: 25
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, dendritic cells, epithelial cells, fibroblasts, lymphocytes, macrophages, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, APC, Biotin
Product options: 4

Product information

Size
Order no.
Price

CD137-APC, human

  • 4B4-1
  • 1:50
  • For research use only
for 30
tests
(1)
130-119-968
-

CD137-APC, human

  • 4B4-1
  • 1:50
  • For research use only
for 100
tests
(1)
130-119-883
-

CD137-Biotin, human

  • 4B4-1
  • 1:50
  • For research use only
for 30
tests
(1)
130-119-969
-

CD137-Biotin, human

  • 4B4-1
  • 1:50
  • For research use only
for 100
tests
(1)
130-119-884
-