CD127 antibodies – functional grade, mouse

CD127 antibodies – functional grade, mouse

Clone: A7R 34
The antibody clone A7R34 reacts with CD127, also known as interleukin 7 receptor α chain (IL-7Rα). Mouse CD127 is a 60–90 kDa type I transmembrane glycoprotein. It is a component of the high affinity IL-7 receptor (IL-7R) and the receptor for thymic stromal lymphopoietin (TSLP). CD127 is expressed on immature B cells, CD4
-
CD8
-
, CD4
+
, and CD8
+
thymocytes, naive and memory T cells, thymic NK cells, and bone marrow stromal cells. Upon activation of naive T cells, CD127 expression is down-regulated. Re-expression of CD127 identifies the effector cells that will differentiate into memory T cells.

Applications

This pure – functional grade antibody is suited for cell culture functional assays, for example, blocking of receptor-ligand binding.

Alternative Names

IL-7R, IL-7Rα

Technical specifications

  • Antigen: CD127
  • Clone: A7R 34
  • Isotype: rat IgG2aκ
  • Alternative names of antigen: IL-7R, IL-7Rα
  • Entrez Gene ID: 16197
  • Molecular mass of antigen [kDa]: 50
  • Distribution of antigen: B cells, bone marrow, liver, lymphocytes, monocytes, T cells, thymocytes
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: -

Product information

Size
Order no.
Price

Related products

3 products available