CD11c antibodies, mouse

CD11c antibodies, mouse

Clone: N418 | Dilution: 1:10
The mouse CD11c antigen is present in dendritic cells in lymphoid organs and blood, in Langerhans cells in the epidermis, in dendritic cell progenitors in the bone marrow, and in
in vitro
generated bone marrow–derived dendritic cells. In spleen and lymph node, CD11c is expressed at high levels on conventional CD11c
+
CD45R
mPDCA-1
dendritic cells, and at moderate levels on CD11c
+
CD45R
+
mPDCA-1
+
plasmacytoid dendritic cells. CD11c is reported to be weakly expressed on NK cells, B cells, and T cell subsets. About 1–3% of splenocytes, 2% of bone marrow cells, as well as <1% of lymph node cells and thymocytes express CD11c.

Alternative Names

ITGAX, CR4, p150, 95, integrin αX, N418

Technical specifications

  • Antigen: CD11c
  • Clone: N418
  • Isotype: hamster IgG
  • Alternative names of antigen: ITGAX, CR4, p150, 95, integrin αX, N418
  • Entrez Gene ID: 16411
  • Molecular mass of antigen [kDa]: 127
  • Distribution of antigen: B cells, dendritic cells, granulocytes, leukemia cells, lymphocytes, macrophages, monocytes, myeloid cells, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
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