CD119 antibodies, human

CD119 antibodies, human

Clone: REA161 | Dilution: 1:11
Clone REA161 recognizes CD119, the alpha chain subunit of the IFN-γ receptor. CD119 is a 80–100 kDa type I transmembrane protein and is responsible for IFN-γ binding. Along with the β chain, CD119 is also involved in signal transduction via STAT1 activation. Except for mature erythrocytes, expression of CD119 is found on the surface of most human cells.
Additional information: Clone REA161 displays negligible binding to Fc receptors.

Alternative names

IFNGR1, Ifngr, IFN-γRα

Technical specifications

  • Antigen: CD119
  • Clone: REA161
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: IFNGR1, Ifngr, IFN-γRα
  • Entrez Gene ID: 3459
  • Molecular mass of antigen [kDa]: 53
  • Distribution of antigen: B cells, T cells, dendritic cells, endothelial cells, macrophages
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Harris, D. P. et al. (2005) Regulation of IFN-γ production by B effector 1 cells: Essential roles for T-bet and the IFN-γ receptor. J. Immunol. 174: 6781-6790
    2. Basler, C. F. et al. (2002) Viruses and the type I interferon antiviral system: induction and evasion. Int. Rev. Immunol. 21(4-5): 305-337
Product options: 12
130-099-929

CD119-FITC, human

for 30
tests
(1)
-
130-099-931

CD119-FITC, human

for 100
tests
(1)
-
130-100-013

CD119-PE, human

for 30
tests
(1)
-
130-099-924

CD119-PE, human

for 100
tests
(1)
-
130-099-920

CD119-APC, human

for 30
tests
(1)
-
130-099-921

CD119-APC, human

for 100
tests
(1)
-
130-099-915

CD119-PE-Vio770, human

for 30
tests
(1)
-
130-099-917

CD119-PE-Vio770, human

for 100
tests
(1)
-
130-099-909

CD119-APC-Vio770, human

for 30
tests
(1)
-
130-099-911

CD119-APC-Vio770, human

for 100
tests
(1)
-
130-100-011

CD119-Biotin, human

for 30
tests
(1)
-
130-099-932

CD119-Biotin, human

for 100
tests
(1)
-