CD117 antibodies, mouse

CD117 antibodies, mouse

Clone: 3C11 | Dilution: 1:10
Clone 3C1 recognizes mouse CD117, a 145 kDa cell surface glycoprotein belonging to the class III receptor tyrosine kinase family. CD117 is also known as c-kit and stem cell factor (SCF) receptor. It is expressed on the majority of hematopoietic progenitor cells including multipotent hematopoietic stem cells as well as some committed myeloid, erythroid and lymphoid precursor cells, and mature mast cells. CD117
+
stem cells from murine bone marrow could also be differentiated into smooth muscle cells, myocytes, and endothelial cells
in vivo
.
1,2

Alternative names

c-kit, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, KIT, SCFR

Technical specifications

  • Antigen: CD117
  • Clone: 3C11
  • Isotype: rat IgG2bκ
  • Isotype control: Rat IgG2b – isotype control antibodies
  • Alternative names of antigen: c-kit, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, KIT, SCFR
  • Entrez Gene ID: 16590
  • Molecular mass of antigen [kDa]: 107
  • Distribution of antigen: B cells, bone marrow, brain, cancer stem cells, dendritic cells, endothelial cells, fibroblasts, hematopoietic stem cells, kidney, leukemia cells, liver, lung, mast cells, megakaryocytes, myeloid cells, NK cells, red blood cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Orlic, D. (2002) Stem cell repair in ischemic heart disease: an experimental model. Int. J. Hematol. 76(suppl.1): 144-145
    2. Orlic, D. et al. (2001) Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc. Natl. Acad. Sci. U.S.A. 98: 10344-10349
Product options: 8
130-102-795

CD117-PE, mouse

9 µg in 300 µL (1)
-
130-102-542

CD117-PE, mouse

30 µg in 1 mL (1)
-
130-102-796

CD117-APC, mouse

9 µg in 300 µL (1)
-
130-102-492

CD117-APC, mouse

30 µg in 1 mL (1)
-
130-108-384

CD117-PE-Vio770, mouse

9 µg in 300 µL (1)
-
130-108-355

CD117-PE-Vio770, mouse

30 µg in 1 mL (1)
-
130-102-000

CD117-Biotin, mouse

9 µg in 300 µL (1)
-
130-101-930

CD117-Biotin, mouse

30 µg in 1 mL (1)
-