CD115 antibodies, mouse

CD115 antibodies, mouse

Dilution: 1:10
Clone AFS98 recognizes the protein tyrosine kinase transmembrane receptor for macrophage colony-stimulating factor (M-CSF), also known as CSF-1 and interleukin 34 (IL-34). CD115 is a single-pass type I membrane protein. Receptor activation induces homo-dimerization, which leads to phosphorylation and ubiquitinylation of intracellular residues. CD115 is expressed on mouse monocytes, macrophages, and osteoclasts, as well as on common dendritic cell precursors and macrophage/dendritic cell precursors.

Alternative Names

Csfmr, Fim-2, FMS, M-CSFR, CSF-1R, c-fms

Technical specifications

  • Antigen: CD115
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: Csfmr, Fim-2, FMS, M-CSFR, CSF-1R, c-fms
  • Entrez Gene ID: 12978
  • Molecular mass of antigen [kDa]: 107
  • Distribution of antigen: breast, dendritic cells, macrophages, myeloid leukemia cells, osteoclasts, smooth muscle
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
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