CD110 antibodies, human

CD110 antibodies, human

Clone: REA250 | Dilution: 1:11
Clone REA250 recognizes the CD110 antigen, a type I transmembrane protein and a member of the hematopoietin receptor family, which is also known as myeloproliferative leukemia protein (MPL) or thrombopoietin receptor (TPO-R). CD110 is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets. It serves as a receptor for thrombopoietin and CD110 deficiency leads to severe thrombocytopenia, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation.
Additional information: Clone REA250 displays negligible binding to Fc receptors.

Alternative Names

MPL, C-MPL, MPLV, THCYT2, TPOR

Technical specifications

  • Antigen: CD110
  • Clone: REA250
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: MPL, C-MPL, MPLV, THCYT2, TPOR
  • Distribution of antigen: platelets, megakaryocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD110-PE, human

  • REA250
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-648
-

CD110-PE, human

  • REA250
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-743
-

CD110-APC, human

  • REA250
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-647
-

CD110-APC, human

  • REA250
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-644
-

CD110-PE-Vio770, human

  • REA250
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-649
-

CD110-PE-Vio770, human

  • REA250
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-744
-

CD110-Biotin, human

  • REA250
  • 1:11
  • For research use only
for 30
tests
(1)
130-111-660
-

CD110-Biotin, human

  • REA250
  • 1:11
  • For research use only
for 100
tests
(1)
130-111-581
-

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