CD107a (LAMP-1) antibodies, human

CD107a (LAMP-1) antibodies, human

Clone: REA792 | Dilution: 1:50
Clone REA792 recognizes the CD107a antigen, also known as lysosome-associated membrane protein 1 (LAMP-1), a 110–140 kDa type I membrane glycoprotein. It is a widely expressed intracellular protein, located in the lysosomal/endosomal membrane. CD107a transiently located on the plasma membrane can be used as a marker for CD8
+
T cell degranulation following stimulation. It is also expressed to a lower extent on activated NK cells.
Additional information: Clone REA792 displays negligible binding to Fc receptors.

Alternative Names

LAMP-1, LAMPA, LGP120, LAMP1

Technical specifications

  • Antigen: CD107a (LAMP-1)
  • Clone: REA792
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: LAMP-1, LAMPA, LGP120, LAMP1
  • Entrez Gene ID: 3916
  • Molecular mass of antigen [kDa]: 42
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    pigtail monkey (
    Macaca nemestrina
    )
    ,
    african green monkey (
    Chlorocebus aethiops
    )
    , baboon,
    chimpanzee (
    Pan troglodytes
    )
  • Distribution of antigen: dendritic cells, endothelial cells, epithelial cells, granulocytes, macrophages, neutrophils, platelets, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Vio667, Biotin
  • Selected References

    1. Fukuda, M. et al. (1988) Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences. J. Biol. Chem. 263(35): 18920-18928
    2. Mane, S. M. et al. (1989) Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys. 268(1): 360-378
    3. Betts, M. R. et al. (2003)
      Sensitive and viable identification of antigen-specific CD8
      +
      T cells by a flow cytometric assay for degranulation.
      J. Immunol. Methods 281: 65-78
Product options: 24
130-111-698

CD107a (LAMP-1)-FITC, human

for 30
tests
(1)
-
130-111-620

CD107a (LAMP-1)-FITC, human

for 100
tests
(1)
-
130-111-699

CD107a (LAMP-1)-PE, human

for 30
tests
(1)
-
130-111-621

CD107a (LAMP-1)-PE, human

for 100
tests
(1)
-
130-112-000

CD107a (LAMP-1)-APC, human

for 30
tests
(1)
-
130-111-847

CD107a (LAMP-1)-APC, human

for 100
tests
(1)
-
130-111-706

CD107a (LAMP-1)-VioBlue, human

for 30
tests
(1)
-
130-111-628

CD107a (LAMP-1)-VioBlue, human

for 100
tests
(1)
-
130-111-707

CD107a (LAMP-1)-VioGreen, human

for 30
tests
(1)
-
130-111-629

CD107a (LAMP-1)-VioGreen, human

for 100
tests
(1)
-
130-111-708

CD107a (LAMP-1)-PE-Vio615, human

for 30
tests
(1)
-
130-111-630

CD107a (LAMP-1)-PE-Vio615, human

for 100
tests
(1)
-
130-111-700

CD107a (LAMP-1)-PE-Vio770, human

for 30
tests
(1)
-
130-111-622

CD107a (LAMP-1)-PE-Vio770, human

for 100
tests
(1)
-
130-111-701

CD107a (LAMP-1)-APC-Vio770, human

for 30
tests
(1)
-
130-111-623

CD107a (LAMP-1)-APC-Vio770, human

for 100
tests
(1)
-
130-111-702

CD107a (LAMP-1)-PerCP-Vio700, human

for 30
tests
(1)
-
130-111-624

CD107a (LAMP-1)-PerCP-Vio700, human

for 100
tests
(1)
-
130-111-703

CD107a (LAMP-1)-VioBright 515, human

for 30
tests
(1)
-
130-111-625

CD107a (LAMP-1)-VioBright 515, human

for 100
tests
(1)
-
130-111-704

CD107a (LAMP-1)-Vio667, human

for 30
tests
(1)
-
130-111-626

CD107a (LAMP-1)-Vio667, human

for 100
tests
(1)
-
130-111-697

CD107a (LAMP-1)-Biotin, human

for 30
tests
(1)
-
130-111-619

CD107a (LAMP-1)-Biotin, human

for 100
tests
(1)
-