CD106 (VCAM-1) antibodies, mouse

CD106 (VCAM-1) antibodies, mouse

Clone: REA971 | Dilution: 1:50
Clone REA971 recognizes the mouse CD106 antigen, a 110 kDa single-chain type I glycoprotein, also known as vascular cell adhesion protein 1 (VCAM-1). CD106 is expressed on bone marrow cells, stromal cells, and inflamed vascular endothelium as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Upregulation of CD106 in endothelial cells by inflammatory stimuli and cytokines occurs as a result of increased gene transcription. Primarily, CD106 is an endothelial ligand for very late antigen-4 (VLA-4) or integrin α-4/β-7 and mediates both adhesion and signal transduction. The interactions play a pathophysiologic role in leukocyte adhesion, transmigration, and co-stimulation of T cell proliferation.
Additional information: Clone REA971 displays negligible binding to Fc receptors.

Alternative Names

VCAM1, INCAM-100

Technical specifications

  • Antigen: CD106 (VCAM-1)
  • Clone: REA971
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: VCAM1, INCAM-100
  • Entrez Gene ID: 22329
  • Molecular mass of antigen [kDa]: 79
  • Distribution of antigen: endothelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, Biotin
Product options: 10

Product information

Size
Order no.
Price

CD106 (VCAM-1)-FITC, mouse

  • REA971
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-322
-

CD106 (VCAM-1)-FITC, mouse

  • REA971
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-219
-

CD106 (VCAM-1)-PE, mouse

  • REA971
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-323
-

CD106 (VCAM-1)-PE, mouse

  • REA971
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-220
-

CD106 (VCAM-1)-APC, mouse

  • REA971
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-324
-

CD106 (VCAM-1)-APC, mouse

  • REA971
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-221
-

CD106 (VCAM-1)-PE-Vio615, mouse

  • REA971
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-326
-

CD106 (VCAM-1)-PE-Vio615, mouse

  • REA971
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-223
-

CD106 (VCAM-1)-Biotin, mouse

  • REA971
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-321
-

CD106 (VCAM-1)-Biotin, mouse

  • REA971
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-218
-

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