CD105 antibodies, mouse

CD105 antibodies, mouse

Clone: MJ7/18 | Dilution: 1:10
The CD105 antibody (clone MJ7/18) recognizes the CD105 antigen, also known as endoglin. CD105 is a proliferation-associated and hypoxia-inducible protein, abundantly expressed in angiogenic endothelial cells. In mouse bone marrow, CD105 is also expressed on a population of Sca-1
+
hematopoietic stem cells (HSCs). This population has a long-term repopulating (LTR) capacity and is therefore termed LTR-HSCs
1,2
. Furthermore, on liver sinusoidal endothelial cells (LSEC), CD105 is co-expressed with CD146 (LSEC).

Alternative Names

ENG, Endo, S-endoglin

Technical specifications

  • Antigen: CD105
  • Clone: MJ7/18
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: ENG, Endo, S-endoglin
  • Entrez Gene ID: 13805
  • Molecular mass of antigen [kDa]: 67
  • Distribution of antigen: bone marrow, endothelial cells, leukemia cells, mesenchymal stem cells, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, VioBright 515, Biotin, pure
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