CD103 antibodies, mouse

CD103 antibodies, mouse

Clone: REA789 | Dilution: 1:50
Clone REA789 recognizes the mouse CD103 antigen, a 175 kDa large, type I transmembrane glycoprotein also known as αE integrin. CD103 associates non-covalently with integrin β7 thereby forming the heterodimeric integrin αEβ7. It mediates cell-cell contact and is involved in homing processes by binding to its ligand e-cadherin. CD103 is expressed on >90% of intestinal intraepithelial lymphocytes (IEL), epithelial T cells, and regulatory T cells. Due to its differential expression on dendritic cells from peripheral tissues, it is useful in identifying dendritic cell subsets from intestinal lamina propria, lung, and dermis.
Additional information: Clone REA789 displays negligible binding to Fc receptors

Alternative Names

ITGAE, aM290, alpha-E1, alpha-M290

Technical specifications

  • Antigen: CD103
  • Clone: REA789
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: ITGAE, aM290, alpha-E1, alpha-M290
  • Entrez Gene ID: 16407
  • Molecular mass of antigen [kDa]: 127
  • Distribution of antigen: B cells, breast, leukemia cells, lymphocytes, pancreas, skin, small intestine, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, VioBright 515, Biotin
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