CD103 antibodies, mouse

Clone: 2E7 | Dilution: 1:50
Armenian Hamster IgG Clone 2E7 reacts with mouse CD103, a 175 kDa large, type I transmembrane glycoprotein also known as αE integrin. CD103 associates noncovalently with integrin β7 thereby forming the heterodimeric integrin αEβ7. It mediates cell-cell contact and is involved in homing processes by binding to its ligand e-cadherin. CD103 is expressed on >90% of intestinal intraepithelial lymphocytes (IEL), epithelial T cells and regulatory T cells. Due to its differential expression on dendritic cells from peripheral tissues, it is useful in identifying dendritic cell subsets from intestinal lamina propria, lung and dermis.

Alternative Names

ITGAE, aM290, alpha-E1, alpha-M290

Technical specifications

  • Antigen: CD103
  • Clone: 2E7
  • Isotype: hamster IgG
  • Alternative names of antigen: ITGAE, aM290, alpha-E1, alpha-M290
  • Entrez Gene ID: 16407
  • Molecular mass of antigen [kDa]: 127
  • Distribution of antigen: B cells, breast, leukemia cells, lymphocytes, pancreas, skin, small intestine, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC
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